Deputy Minister of Health Cao Minh Quang has been sacked after just one term for his "violations while in duty," according to the government website.
Quang, 56, had completed a five-year term in February, and was a caretaker deputy minister pending a decision by the government about whether to give him one more term.
The Ministry of Health recommended against it, and is considering a new assignment for him.
Earlier this year the Communist Party's inspectorate had issued a warning to Quang for not abiding by the criteria for being a member, thus harming the Party's internal unity as well as his own reputation.
Inspectors said that in 2007 Quang got the Ho Chi Minh City-based BV Pharma Joint-venture Co. to lend him VND1 billion (US$48,000), which was motivated by "self-interest."
He also falsely declared that he had a doctorate from Uppsala University in Sweden in 1996.
Following accusations by a war veteran last year, the Ministry of Education and Training launched an investigation and found that he only had a pre-doctorate degree.
According to inspectors, he also made erroneous statements and reports to the ministry, and flouted regulations by making "arbitrary" assessments that "failed to mention" his subordinates.
In 2009 too Quang was warned by the inspectorate for several violations, including making false accusations against the US-owned Merck Sharp and Dohme (MSD) Company in Vietnam.
He wrote to MSD's CEO and administrative president for the Asia-Pacific region complaining about the company's unethical lobbying for a vaccine against human papillomavirus, according to the inspectorate.