A three-year-old girl infected with the influenza A (H5N1) virus, died in Ho Chi Minh City on Wednesday, bringing the country's avian flu death toll to 59 since 2003.
The child, whose name wasn't revealed, was admitted to Children's Hospital No.2 last Wednesday with the symptoms of dengue fever but later developed pneumonia.
She tested positive for bird flu on Monday.
Her condition worsened and she died of respiratory failure and critical pneumonia early Wednesday morning.
Doctors said her family lived in a rented house nearby a market where chickens were sold in the adjacent Binh Duong Province's Thuan An District.
It was the second H5N1-related death recorded this year in the country, with the first reported last month.
Since 2003, 116 people have been infected by bird flu in Vietnam, including five this year.
Vietnam recorded five avian flu patients last year, all of whom died.